高频超声造影在浅表肝脏局灶性病变检出及诊断中的临床价值
Clinical value of high-frequency contrast-enhanced ultrasound in the detection and diagnosis of superficial focal liver lesions
何玉虹 1闻宝杰 1于鹏丽 1王文平 2孔文韬1
作者信息
- 1. 210009 南京市,南京大学医学院附属鼓楼医院超声医学科
- 2. 复旦大学附属中山医院超声科
- 折叠
摘要
目的 探讨高频超声造影(CEUS)在浅表肝脏局灶性病变(FLLs)检出及诊断中的临床价值.方法 选取我院浅表FLLs患者38例,共63个病变,分别使用低频凸阵探头和高频线阵探头对患者进行CEUS检查,比较低频CEUS与高频CEUS在病变可见度评分、检出率和良恶性鉴别诊断中的差异.结果 浅表FLLs在高频CEUS下平均可见度评分和检出率分别为(3.62±0.79)分、93.7%(59/63),均显著高于低频CEUS[(2.44±1.04)分、57.1%(36/63)],差异均有统计学意义(均P<0.05).高频CEUS对最大径≤1 cm FLLs、最大径1～2 cm FLLs和肝转移瘤的检出率均显著高于低频CEUS[96.7%(29/30)vs.46.7%(14/30)、92.6%(25/27)vs.66.7%(18/27)、100%(26/26)vs.57.7%(15/26)],差异均有统计学意义(均P<0.001).高频CEUS鉴别诊断浅表FLLs良恶性的灵敏度、准确率分别为92.9%、91.7%,均高于低频CEUS(78.6%、77.8%),差异均有统计学意义(均P<0.05).结论 高频CEUS在提高浅表FLLs的检出率和定性诊断方面均有明显优势,具有重要的临床价值.
Abstract
Objective To investigate the clinical value of high-frequency contrast-enhanced ultrasound(CEUS)in the detection and diagnosis of superficial focal liver lesions(FLLs).Methods Thirty-eight patients with 63 FLLs in our hospital were included.CEUS examinations were performed using a low-frequency convex array probe and a high-frequency linear array probe.The difference in lesion visibility score,detection rate and benign and malignant diagnosis between low-frequency CEUS and high-frequency CEUS were compared.Results The average visibility scores and detection rates of superficial FLLs by high-frequency CEUS were(3.62±0.79)points and 93.7%(59/63),respectively,which were higher than those by low-frequency CEUS[(2.44±1.04)points,57.1%(36/63)],and the differences were statistically significant(both P<0.05).High-frequency CEUS demonstrated significantly higher detection rates for lesions with a maximum diameter≤1 cm[96.7%(29/30)vs.46.7%(14/30)],lesions with a diameter of 1～2 cm[92.6%(25/27)vs.66.7%(18/27)]and liver metastases[100%(26/26)vs.57.7%(15/26)]compared with low-frequency CEUS,and the differences were statistically significant(all P<0.001).The sensitivity and accuracy of high-frequency CEUS in the differential diagnosis of benign and malignant superficial FLLs were 92.9%and 91.7%,respectively,which were higher than those of low-frequency CEUS(78.6%,77.8%),and the differences were statistically significant(both P<0.05).Conclusion High-frequency CEUS offers distinct advantages in improving the detection rate and qualitative diagnostic efficacy of superficial FLLs,demonstrating significant clinical value.
关键词
超声检查,高频,低频/造影剂/肝脏局灶性病变,良恶性Key words
Ultrasonography,high-frequency,low-frequency/Contrast agent/Focal liver lesion,benign and malignant引用本文复制引用
基金项目
南京鼓楼医院临床研究专项资金项目——面上项目(2022-LCYJ-MS-24)
出版年
2024
NETL
NSTL
万方数据