Clinical value of four-dimensional automatic left atrial quantitative technology in evaluating left atrium structure and function in patients with masked uncontrolled hypertension
Objective To explore the clinical application value of four-dimensional automatic left atrial quantification technology(4D-Auto-LAQ)in evaluating left atrial structure and function in patients with masked uncontrolled hypertension(MUHT).Methods A total of 71 patients with masked hypertension who underwent 24 h ambulatory blood pressure monitoring in our hospital were selected,including 34 patients with MUHT(MUHT group)and 37 patients with well-controlled hypertension(WCHT group).Conventional echocardiography was used to obtain the left atrial diameter(LAD),interventricular septal thickness(IVST),left ventricular posterior wall thickness(LVPWT),left ventricular end-diastolic volume(LVEDV),left ventricular ejection fraction(LVEF),mitral orifice early and late diastolic blood flow velocity(E,A),left ventricular wall motion velocity(Lat e')and ventricular septal motion velocity(Sep e'),the average of Lat e'and Sep e'(e')and E/e'were calculated.4D-Auto-LAQ was used to obtain left atrial volume parameters and left atrial strain parameters,including left atrial maximum volume index(LAVImax),left atrial pre-systolic volume index(LAVIpreA),left atrial minimum volume index(LAVImin),left atrial total ejection fraction(LAEF),left atrial passive ejection fraction(LApEF),left atrial active ejection fraction(LAaEF),left atrial reserve phase strain(LASr),left atrial conduit phase strain(LAScd)and left atrial systolic strain(LASct).The differences of the above parameters between the two groups were compared.The correlation between LASr,LAScd,LASct and E/e'were analyzed.Results Compared with WCHT group,Lat e',Sep e'and e'in MUHT group were decreased,while E/e'was increased,and the differences were statistically significant(all P<0.05).There were no significant differences in LAD,IVST,LVPWT,LVEDV,LVEF,E and A between MUHT group and WCHT group.Compared with WCHT group,LAVImax,LAVIpreA,LAVImin and LAaEF in MUHT group were increased,while LApEF,LASr,LAScd and LASct were decreased,and the differences were statistically significant(all P<0.05).Correlation analysis showed that LASr was positively correlated with E/e'(r=0.393,P<0.001),while LAScd and LASct were not significantly correlated with E/e'.Conclusion 4D-Auto-LAQ can be used for early detection of left atrial structure and function changes in MUHT patients,which has certain clinical application value.
EchocardiographyFour-dimensional automatic left atrial quantification technologyMasked uncontrolled hypertensionAtrial function,left
NETL
NSTL
万方数据
