Clinical value of pancreatic-splenic ultrasound gray-scale ratio in the diagnosis of non-alcoholic fatty pancreas disease and influencing factors analysis
Clinical value of pancreatic-splenic ultrasound gray-scale ratio in the diagnosis of non-alcoholic fatty pancreas disease and influencing factors analysis
Objective To analyze the relevant influencing factors of pancreatic-splenic ultrasound grayscale ratio(UGSR)measured and calculated by ultrasound gray-scale histogram,and to assess the clinical value the diagnosis of non-alcoholic fatty pancreas disease(NAFPD).Methods Ninety-five inpatients patients who underwent abdominal CT and ultrasound at our hospital were selected.According to the CT diagnostic results,all patients were divided into the NAFPD group(44 cases)and the non-NAFPD group(51 cases).The average gray-scale value of the region of interest(ROI)of the pancreas and spleen were measured by gray-scale histograms,and the ratio of these values was calculated as the pancreatic-splenic UGSR.The differences of pancreatic-splenic UGSR and clinical data between the two groups were compared.Univariate and multivariate linear regression analysis were used to screen the influencing factors of pancreatic-splenic UGSR.Receiver operating characteristic(ROC)curve was drawn to evaluate the diagnostic performance of pancreatic-splenic UGSR for NAFPD.Results There were statistically significant differences in age,body mass index(BMI),systolic blood pressure,diastolic blood pressure,fasting blood glucose(FBG),triglycerides(TG),total cholesterol(TC),high-density lipoprotein,low-density lipoprotein(LDL),alanine aminotransferase and pancreatic-splenic UGSR between the NAFPD group and the non-NAFPD group(all P<0.05),while there were no statistically significant differences in gender and aspartate aminotransferase.Univariate linear regression analysis indicated that age,BMI,blood pressure,FBG,TG,TC and LDL were influencing factors of pancreatic-splenic UGSR(all P<0.05).Multivariate linear regression analysis showed that BMI and FBG were independent influencing factors of pancreatic-splenic UGSR(both P<0.05).ROC curve analysis showed that the area under the curve of pancreatic-splenic UGSR for diagnosing NAFPD was 0.929(95%confidence interval:0.858～0.972),with a cutoff value of 1.64,corresponding to a sensitivity of 97.73%and a specificity of 88.24%.Conclusion The pancreatic-splenic UGSR measured and calculated by ultrasound gray-scale histogram demonstrates a certain clinical value for NAFPD,and both BMI and FBG are independent influencing factors of pancreatic-splenic UGSR.
维普
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