Objective To explore the value of ultrasound in the diagnosis of rotator cuff injury,and to analyze the clinical application value of constructed predictive model in predicting the prognosis in the patients with rotator cuff injury.Methods A retrospective analysis was conducted on the clinical data and ultrasound image features of 82 patients who were suspected of rotator cuff injury and admitted to the hospital from February 2021 to June 2023.The consistency between diagnostic results of musculoskeletal ultrasound and arthroscopy was evaluated.Univariate and multivariate Logistic regression analysis were used to screen the influencing factors for the prognosis of patients with rotator cuff injury,and a predictive model was constructed.Receiver operating characteristic(ROC)curve was drawn to analyze the efficacy of the model in predicting the prognosis in patients with rotator cuff injury.Another 21 patients with rotator cuff injury admitted to the hospital from July to November 2023 were selected for clinical external validation.Results Among the 82 included patients with suspected rotator cuff injury,73 were diagnosed as rotator cuff injury by arthroscopy.The sensitivity,specificity and accuracy of ultrasound for diagnosing rotator cuff injury were 90.41%,88.89%and 90.24%,respectively.The consistency with arthroscopy was at a middle level(Kappa=0.614).Among 73 patients with rotator cuff injury,59 patients had good prognosis and 14 patients had poor prognosis.Univariate and multivariate Logistic regression analysis showed that age,the degree of rotator cuff tear and the degree of rotator cuff muscle atrophy were independent risk factors for predicting the poor prognosis in patients with rotator cuff injury(OR=1.634,2.869,2.389,all P<0.05).A predictive model for predicting the prognosis in patients with rotator cuff injury was constructed.The area under the ROC curve of the model was 0.805(95%confidence interval:0.691~0.919,P<0.001),the sensitivity and specificity were 71.43%and 77.97%,respectively.Clinical external validation showed that the accuracy of the model for predicting the prognosis in patients with rotator cuff injury was 80.95%,and the consistency with clinical diagnosis results was at a moderate level(Kappa=0.481).Conclusion Ultrasound has high value in the diagnosis of rotator cfuff injury.The predictive model constructed on age,the degree of rotator cuff tear and the degree of rotator cuff muscle atrophy has a certain value in predicting the prognosis in patients with rotator cuff injury.