Clinical value of RF-data based quantitative analysis on vessel stiffness in the evaluation of carotid artery stiffness in patients with Hashimoto's thyroiditis
Objective To explore the clinical application value of RF-data based quantitative analysis on vessel stiffness(R-VQS)in the evaluation of carotid artery stiffness in patients with Hashimoto's thyroiditis(HT).Methods A total of 73 female patients with HT were selected from our hospital and divided into two groups according to thyroid function:the abnormal thyroid function HT group(n=38)and the normal thyroid function HT group(n=35).50 age-matched healthy females were included as control group.The differences of general data,serum indicators and carotid artery ultrasonic parameters among groups were compared.The correlation between carotid artery ultrasonic parameters and general data,serum indicators were analyzed,the repeatability test was used to evaluate the consistency of carotid ultrasonic parameters measured by inter-and intra-observer.Results There were significant differences in systolic blood pressure,diastolic blood pressure,pulse pressure and high-density lipoprotein among groups(all P<0.05).There were significant differences in common carotid artery systolic diameter,stiffness index and pulse wave velocity among groups(all P<0.05),while the comparison of intima-media thickness and vessel wall displacement showed no statistical difference.Correlation analysis showed that common carotid artery systolic diameter was positively correlated with systolic blood pressure,pulse pressure,and negatively correlated with high-density lipoprotein(all P<0.05).Pulse wave velocity was positively correlated with systolic blood pressure and pulse pressure,and negatively correlated with diastolic blood pressure and high-density lipoprotein(all P<0.05).The inter-and intra-observer consistency of the measurement of common carotid artery parameters such as systolic diameter,stiffness index,pulse wave velocity,intima-media thickness,vessel wall displacement were good(all P<0.05).Conclusion R-VQS can evaluate carotid artery stiffness and carotid artery lesions in HT patients effectively,which has a certain clinical application value.
RF-data based quantitative analysis on vessel stiffnessHashimoto's thyroiditisCarotid artery stiffnessCarotid artery
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