Malignant tumors exhibit a high incidence rate and unfavorable prognosis,and it is particularly important to explore novel and effective treatment modalities.In recent years,ultrasound cavitation has emerged as a promising non-invasive therapeutic approach in cancer management.This article comprehensively summarizes the latest research advancements and clinical application progress of ultrasonic cavitation from both domestic and international perspectives.Furthermore,it critically analyzes the application patterns,therapeutic efficacy and influencing factors in the treatment of malignant tumor,aiming to provide new strategic insights for the clinical treatment of malignant tumors.