首页|先天性耳廓形态畸形及其不同分型的危险因素分析

先天性耳廓形态畸形及其不同分型的危险因素分析

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目的:探讨先天性耳廓形态畸形的发病特点、高危因素及不同类型形态畸形之间高危因素的差异,为耳廓形态畸形的精准防控提供理论依据.方法:对2022年5月—2023年1月于郑州大学第二附属医院足月出生的新生儿行耳廓畸形筛查,收集信息资料,自制问卷进行高危因素调查,采用病例对照研究方法,以耳廓形态畸形的新生儿为病例组,选取同期无耳廓形态畸形的新生儿作为对照组,分析耳廓形态畸形的发生率、高危因素及不同类型耳廓形态畸形高危因素的差异.结果:本研究共纳入1 758例新生儿(3 516耳),耳廓形态畸形新生儿562例,共927耳,先天性耳廓形态畸形的发生率为26.37%.其中耳轮畸形289耳(8.22%)、垂耳244耳(6.94%)、混合畸形166耳(4.72%)、招风耳/杯状耳131耳(3.73%)、Stahl's耳79耳(2.25%)、耳甲腔异常凸起16耳(0.46%)、隐耳2耳(0.06%).母亲孕早期感染史(OR=1.513,95%CI 1.119~2.045)、既往流产史(OR=1.300,95%CI 1.049~1.613)、异常妊娠(OR=1.278,95%CI 1.032~1.582)是先天性耳廓形态畸形的危险因素.耳轮畸形、垂耳和混合畸形在母亲孕早期感染史(x2=1.877,P=0.391)、既往流产史(x2=4.706,P=0.095)、异常妊娠(x2=5.026,P=0.081)差异无统计学意义.结论:先天性耳廓形态畸形发生率高,以耳轮畸形、垂耳、混合畸形较为常见,耳廓形态畸形由多种因素导致,同一危险因素对不同类型形态畸形的影响大致相同.
Analysis of risk factors for congenital auriclar deformity and its different types
Objective:To Explore the clinical characteristics,risk factors,and differences in risk factors for different types of congenital auricular deformities,in order to provide theoretical basis for precise prevention and control of congeni-tal auriclar deformity.Methods:Full-term newborns born in the Second Affiliated Hospital of Zhengzhou University from May 2022 to January 2023 were screened for auricle malformation,general information and data were collected,,and high-risk factors were investigated withself-made questionnaire.Using a case-control study method,newborns with auriclar de-formities were selected as the case group and those without auriclar deformities during the same period were selected as the control group.A case-control study was conducted to analyze the incidence rate,high-risk factors,and differences in high-risk factors for different types of auricle deformities.Results:A total of 1 758 newborns(3 516 ears)were included in this study,including 562 newborns(927 ears)with auriclar deformities,the incidence of congenital malformations of the auricle is 26.37%.Among them,289 ears(8.22%)were helical rim deformity,244 ears(6.94%)were lidding/lop ear,166 ears(4.72%)were mixed deformities,131 ears(3.73%)were prominent/cup ear,79 ears(2.25%)were Stahl's ears,16 ears(0.46%)were abnormal conchal crus,and 2 ears(0.06%)were cryptotia.Maternal history of infection in early pregnancy(OR=1.513,95%CI 1.119-2.045),previous miscarriage history(OR=1.300,95%CI 1.049-1.613),and abnormal pregnancy(OR=1.278,95%CI 1.032-1.582)are risk factors for congenital auricular malformations.There was no statistically significant difference in the history of infection(x2=1.877,P=0.391),previous miscarriage(x2=4.706,P=0.095),and abnormal pregnancy(x2=5.026,P=0.081)among mothers with helical rim deformity,lid-ding/lop ear,and mixed deformities.Conclusion:The incidence rate of congenital auricle deformity is high,with common malformations such as helical rim deformity,lidding/lop ear,and mixed deformities.Congenital auricular deformity is caused by various factors,the same risk factor has roughly the same impact on different types of morphological abnormal-ities.

congenital auriclar deformityincidencerisk factors

王施梦、米彦芳、张慧、陈莹、宋云韬、杨瑾

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郑州大学第二附属医院耳鼻咽喉科(郑州,450003)

先天性耳廓畸形 发生率 危险因素

2024

临床耳鼻咽喉头颈外科杂志
华中科技大学同济医学院附属协和医院

临床耳鼻咽喉头颈外科杂志

CSTPCD北大核心
影响因子:0.831
ISSN:1001-1781
年,卷(期):2024.38(2)
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