Preliminary application of indocyanine green fluorescence imaging technology in nasal endoscopic tumor surgery
Objective:To preliminarily study the practical value of Indocyanine green(ICG)molecular fluores-cence imaging technology in nasal endoscopic tumor surgery.Methods:Five patients with tumors related to nasal sinuses,orbital wall and skull base in the Department of Otolaryngology head and Neck Surgery,General Hospital of Xinjiang Military Command from December 2022 to April 2023 were enrolled.Among them,3 were benign tumors and 2 were malignant tumors.All patients underwent surgery under the guidance of ICG molecular fluo-rescence imaging.ICG was administered intravenously through cubital vein at a dose of 0.5 mg/kg 12 to 24 h be-fore surgery.Tumors were labeled by fluorescence imaging during the operation.surgeons cleared the tumor tis-sue strictly according to the labeled range and depth,malignant tumors were further expanded and cleaned accord-ing to pathology results.Results:All 5 patients achieved accurate tumor localization with the aid of fluorescence imaging technology.Resections were performed with reference to fluorescent labeling boundaries,all patients a-chieved complete tumor cleanup or negative margins.Conclusion:For tumor-related surgery under nasal endosco-py,ICG molecular fluorescence imaging technology can not only achieve accurate real-time positioning,but also provide evidence for surgeons to judge tumor boundaries.Therefore,we believe that the technology should have certain practical value in nasal endoscopic tumor surgery.
skull base tumorfluorescent dyeindocyanine greendiagnostic imagingnasal cavityendo-scopic surgery
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