Research progress in targeted delivery of inner ear using nanocarriers
Various inner ear diseases such as sensorineural deafness and Meniere's disease bring about prob-lems such as speech communication disorders and decreased work efficiency,which seriously affect the life quality of patients.Due to the special anatomical structure and blood-labyrinth barrier in the inner ear,the current drug administration methods are often unable to achieve satisfactory results.Nanocarriers are the forefront and hot spot of nanotechnology research.In recent years,a lot of research progress has been made in the field of targeted deliv-ery of the inner ear,which is expected to be eventually applied to the treatment of clinical diseases of the inner ear.This review focuses on the advantages,main research achievements and limitations of various nanocarriers in the targeted delivery of the inner ear,hoping to provide new ideas for related research.