Research advances of mesenchymal stem cell in allergic rhinitis
Allergic rhinitis is a chronic nasal mucosal inflammation characterized by upper airway hyperre-sponsiveness,involving a variety of immune cells and inflammatory mediators.Drugs,immunotherapy,and sur-gical operation are the principal treatments at present.The study found that mesenchymal stem cells have the abil-ity of immune regulation and have a promising clinical application in the treatment of allergic rhinitis.In this re-view,the action mechanism of mesenchymal stem cells,the immunomodulatory effect of mesenchymal stem cells on the key cells of allergic rhinitis,and the challenges of clinical application are reviewed,to provide new direc-tions for the treatment of allergic rhinitis.