Analysis of allergen distribution and indoor factors in allergic rhinitis in Chaoshan area
Objective:To investigate the distribution of common allergens and indoor factors influencing the severity of allergic rhinitis in patients from the Chaoshan region.Methods:Patients diagnosed with allergic rhinitis from Shantou,Jieyang,and Chaozhou were selected for serum allergen-specific IgE testing.A questionnaire sur-vey was conducted to analyze the distribution of allergens and indoor factors affecting the severity of the disease.Results:A total of 1 800 questionnaires were collected,with 1 646 valid responses,resulting in an effective re-sponse rate of 91.4％.Among the 1 646 included patients with allergic rhinitis,there were 1 285 children(≤14 years),361 adolescents and adults(＞14 years);of which 999 were males and 647 were females.The top three al-lergens with the highest positive rates were house dust mites(n=1 457,88.5％),milk(n=569,34.6％),and crab(n=360,21.9％).The proportions of allergen sensitization to house dust mites,house dust,dog dander,egg white,milk,fish,crab,shrimp,and beef showed statistically significant differences between children and ad-olescents and adults(P＜0.01).There were also statistically significant differences in crab and shrimp sensitiza-tion between males and females(P＜0.01).Multivariate analysis revealed that active/passive smoking,religious rituals,air conditioning usage,pet ownership,air purifier usage,and bedding drying were indoor factors influen-cing the severity of allergic rhinitis.Among them,active/passive smoking,religious rituals,air conditioning us-age,and pet ownership were risk factors for exacerbating the disease,while air purifier usage and bedding drying were protective factors.Conclusion:House dust mites are the most common allergen in patients with allergic rhi-nitis in the Chaoshan region.Active/passive smoking,religious rituals,air conditioning usage,and pet ownership can worsen the condition,while air purifier usage and bedding drying can help control the disease.The results of this study can provide clinical reference.
万方数据
维普
