Heterogeneous acellular dermal matrix for wound repair after endoscopic Type-V a cordectomy
Objective:To observe the clinical effect of placing heterogeneous acellular dermal matrix membrane for laryngeal cavity wound healing after CO2 laser Type-V a cordectomy for glottic carcinoma.Methods:Thirty-five patients with bilateral vocal cord laryngeal cancer who underwent endoscopic CO2 laser surgery at the Depart-ment of Otorhinolaryngology Head and Neck Surgery,the Second Xiangya Hospital of Central South University from March 2018 to December 2019 were selected and divided into 2 groups,including 18 patients in the study group and 17 patients in the control group.The control group was simply placed silicone tube stent,while in the study group,heterogeneous acellular dermal matrix membrane was coated with silicone tube stent.The postoper-ative laryngeal wound repair and clinical manifestations were observed and compared between the two groups.Re-sults:Compared postoperative laryngeal wound after 6 months:no patients in the study group had granulation tis-sue,whereas 4 patients in the control group had granulation tissue;3 patients in the study group developed mod-erate to severe tissue adhesion,while 9 patients in the control group;10 patients in the control group developed 2nd to 4th degree laryngeal obstruction,compared with only 4 patients in the study group.Conclusion:The pri-mary placement of ADM can reduce laryngeal granulation tissue and tissue adhesion after CO2 laser Type-V a cordectomy for laryngeal cancer,and may reduce the occurrence of postoperative laryngeal obstruction.
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