Analysis of the difference of therapeutic effect and predictive factors between postural and non-postural OSA after modified uvulopalatopharyngoplasty
Objective:To analyze the factors influencing the outcome of uvulopalatopharyngoplasty in position-al obstructive sleep apnea(POSA)and non-positional OSA(NPOSA)patients,and to explore the differences be-tween the two groups.Methods:The data of 101 patients with obstructive sleep apnea who received treatment from November 2020 to November 2023 were retrospectively analyzed.Among them,45 positional patients(PO-SA group)and 56 non-positional patients(NPOSA group),who underwent overnight polysomnography were in-cluded.The upper airway(UA)anatomy was evaluated by three-dimensional computer tomography(3D-CT).All patients received revised uvulopalatopharyngoplasty with uvula preservation and were followed using polysomnog-raphy for at least three months postoperatively.Results:The overall effective rate was 55.45%.The surgical suc-cess rate in POSA undergoing UPPP was higher than NPOSA(POSA 30/45,66.7%versus NPOSA 26/56,46.4%,P=0.042).The H-UPPP effect of POSA was negatively correlated with the minimum lateral airway of the Velopharyngeal airway(r=-0.505,P<0.001),the minimum lateral airway of the glossopharyngeal airway(r=-0.474,P=0.001)and the minimum cross-sectional area(r=-0.394,P=0.007).Logistic analysis showed that minimal lateral airway of the glossopharynxgeum(mLAT)(OR 0.873;95%CI 0.798-0.955,P=0.003)was a significant predictor for surgical outcomes among POSA patients.In NPOSA,age(OR 0.936;95%CI 0.879-0.998,P=0.042)was a significant predictor for surgical outcomes.Conclusion:The effect of H-UPPP was higher in POSA than in NPOSA.The width of glossopharyngeal mLAT was an important predictor of POSA efficacy.Age was a predictor of NPOSA efficacy.