Analysis of risk factors for lymph node metastasis in patients with CN0 papillary thyroid carcinoma
Objective:To explore the risk factors of lymph node metastasis and multiple lymph node metasta-sis in patients with stage CN0 papillary thyroid carcinoma.Methods:The clinical case data of 3 099 patients with CN0 papillary thyroid cancer who underwent lymph node dissection at Xijing Hospital of Air Force Medical Uni-versity from January 2013 to December 2022 were retrospectively analyzed,univariate and multivariate logistic re-gression were used to analyze the risk factors of lymph node metastasis and multiple lymph node metastasis.Re-sults:Male gender,age<55 years,multifocal lesions,and lesion size ≥2 cm were independent risk factors for lymph node metastasis in CN0 patients(P<0.05),while diabetes was an independent protective factor for lymph node metastasis(P<0.05).Age<55 years,capsular invasion,and multifocal lesions were independent risk fac-tors for the presence of ≥3 lymph nodes with metastasis(P<0.05).Conclusion:In CN0 stage PTC patients,special attention should be given to the possibility of lymph node metastasis when they are male,aged<55 years,have multifocal lesions,or have lesion size>2 cm.