摘要
目的:探讨CN0期甲状腺乳头状癌(PTC)患者淋巴结转移及多枚淋巴结转移的危险因素.方法:回顾性分析2013年1月-2022年12月空军军医大学西京医院行淋巴结清扫的3 099例CN0期PTC患者临床资料,单因素及多因素logistic回归分析淋巴结转移及多枚淋巴结转移的危险因素.结果:男性、年龄＜55岁、多灶病灶、病灶大小＞2 cm是CN0期PTC患者淋巴结转移的独立危险因素(P＜0.05),而合并糖尿病是淋巴结转移的独立保护因素(P＜0.05).年龄＜55岁、包膜侵犯、多灶病灶是淋巴结数目≥3枚的独立危险因素(P＜0.05).结论:当CN0期PTC患者为男性、年龄＜55岁、多灶病灶、病灶大小＞2 cm时,要高度警惕淋巴结转移的可能性.
Abstract
Objective:To explore the risk factors of lymph node metastasis and multiple lymph node metasta-sis in patients with stage CN0 papillary thyroid carcinoma.Methods:The clinical case data of 3 099 patients with CN0 papillary thyroid cancer who underwent lymph node dissection at Xijing Hospital of Air Force Medical Uni-versity from January 2013 to December 2022 were retrospectively analyzed,univariate and multivariate logistic re-gression were used to analyze the risk factors of lymph node metastasis and multiple lymph node metastasis.Re-sults:Male gender,age＜55 years,multifocal lesions,and lesion size ≥2 cm were independent risk factors for lymph node metastasis in CN0 patients(P＜0.05),while diabetes was an independent protective factor for lymph node metastasis(P＜0.05).Age＜55 years,capsular invasion,and multifocal lesions were independent risk fac-tors for the presence of ≥3 lymph nodes with metastasis(P＜0.05).Conclusion:In CN0 stage PTC patients,special attention should be given to the possibility of lymph node metastasis when they are male,aged＜55 years,have multifocal lesions,or have lesion size＞2 cm.
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