首页|生物膜-硅胶喉模复合体在防治声带粘连中的临床应用分析

生物膜-硅胶喉模复合体在防治声带粘连中的临床应用分析

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目的:探讨生物膜联合喉模技术在声带粘连的预防和治疗中的临床效果.方法:回顾性分析复旦大学附属华山医院诊治的21例接受生物膜-硅胶喉模复合体技术防治声带粘连患者的基本资料、围手术期一般情况及治疗预后.结果:纳入21例患者中男19例(90.5%),女2例(9.5%),其中18例早期声门型喉癌(T1b)、1例双侧声带白斑及2例喉术后声带粘连患者.围术期均未发生喉模意外脱离,术后平均(22.4±2.6)d拆除硅胶模.术后定期复查,整体有效率为90.5%(19/21).术后5例患者出现并发症(1例喉内感染、4例肉芽组织增生),经保守治疗后均痊愈.结论:本研究初步探索了生物膜材料在防治声带粘连中的可行性,该生物膜-硅胶喉模复合体技术操作简便,预防声带粘连效果良好,值得临床推广.
Clinical analysis of biomaterial-silicone keel complex in the vocal folds adhesion treatment
Objective:To retrospectively analyze the clinical effect of biomaterial combined with silicone keel technology in the prevention and treatment of vocal folds adhesion.Methods:The basic data,perioperative condi-tions and prognosis of 21 cases of vocal folds adhesion treated by biofilm-silicone keel complex were retrospectively analyzed in Huashan Hospital Fudan University.Results:A total of 21 patients were enrolled in this study(19 males(90.5%),2 females(9.5%).Among these patients,18 cases of early glottic laryngeal carcinoma(T1b),1 case of bilateral vocal folds leukoplecta and 2 cases of postoperative vocal folds adhesion.No accidental rupture of the silicone keel occurred during perioperative period,and the silicone keel was removed in 22.4±2.6 days.All patients were reviewed after removing the silicone keel,the overall effective rate was 90.5%(19/21).Postopera-tive complications occurred in 5 patients(1 laryngeal infection,4 granulation tissue hyperplasia),all of whom were cured after conservative treatment.Conclusion:This study explored the feasibility of biomaterial in the treatment of vocal folds adhesion.The biomaterial-silicone keel complex technology is simple to operate and has effect on the prevention of vocal folds adhesions,which is worth of clinical promotion.

vocal folds adhesionbiomaterialthe keeltreatment

李旭茂、谢予晖、陈翔宇、崔西栋、孙广滨

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复旦大学附属华山医院耳鼻咽喉头颈外科(上海,200040)

声带粘连 生物膜 喉模 治疗

国家自然科学基金

82271154

2024

临床耳鼻咽喉头颈外科杂志
华中科技大学同济医学院附属协和医院

临床耳鼻咽喉头颈外科杂志

CSTPCD北大核心
影响因子:0.831
ISSN:1001-1781
年,卷(期):2024.38(10)