生物膜-硅胶喉模复合体在防治声带粘连中的临床应用分析
Clinical analysis of biomaterial-silicone keel complex in the vocal folds adhesion treatment
李旭茂 1谢予晖 1陈翔宇 1崔西栋 1孙广滨1
作者信息
- 1. 复旦大学附属华山医院耳鼻咽喉头颈外科(上海,200040)
- 折叠
摘要
目的:探讨生物膜联合喉模技术在声带粘连的预防和治疗中的临床效果.方法:回顾性分析复旦大学附属华山医院诊治的21例接受生物膜-硅胶喉模复合体技术防治声带粘连患者的基本资料、围手术期一般情况及治疗预后.结果:纳入21例患者中男19例(90.5％),女2例(9.5％),其中18例早期声门型喉癌(T1b)、1例双侧声带白斑及2例喉术后声带粘连患者.围术期均未发生喉模意外脱离,术后平均(22.4±2.6)d拆除硅胶模.术后定期复查,整体有效率为90.5％(19/21).术后5例患者出现并发症(1例喉内感染、4例肉芽组织增生),经保守治疗后均痊愈.结论:本研究初步探索了生物膜材料在防治声带粘连中的可行性,该生物膜-硅胶喉模复合体技术操作简便,预防声带粘连效果良好,值得临床推广.
Abstract
Objective:To retrospectively analyze the clinical effect of biomaterial combined with silicone keel technology in the prevention and treatment of vocal folds adhesion.Methods:The basic data,perioperative condi-tions and prognosis of 21 cases of vocal folds adhesion treated by biofilm-silicone keel complex were retrospectively analyzed in Huashan Hospital Fudan University.Results:A total of 21 patients were enrolled in this study(19 males(90.5％),2 females(9.5％).Among these patients,18 cases of early glottic laryngeal carcinoma(T1b),1 case of bilateral vocal folds leukoplecta and 2 cases of postoperative vocal folds adhesion.No accidental rupture of the silicone keel occurred during perioperative period,and the silicone keel was removed in 22.4±2.6 days.All patients were reviewed after removing the silicone keel,the overall effective rate was 90.5％(19/21).Postopera-tive complications occurred in 5 patients(1 laryngeal infection,4 granulation tissue hyperplasia),all of whom were cured after conservative treatment.Conclusion:This study explored the feasibility of biomaterial in the treatment of vocal folds adhesion.The biomaterial-silicone keel complex technology is simple to operate and has effect on the prevention of vocal folds adhesions,which is worth of clinical promotion.
关键词
声带粘连/生物膜/喉模/治疗Key words
vocal folds adhesion/biomaterial/the keel/treatment引用本文复制引用
出版年
2024
NETL
NSTL
万方数据