Comparative analysis of audiovestibular testing results in vestibular schwannomas
Objective:This study aimed to analyze the results of auditory and vestibular function tests in pa-tients with unilateral vestibular schwannoma and explore their association with tumor size.Methods:Clinical data from 81 patients diagnosed with unilateral vestibular schwannoma who underwent pure-tone audiometry(PTA),cervical and ocular vestibular evoked myogenic potentials(c/oVEMP),as well as video head impulse test(vHIT),and subsequently underwent surgical treatment,were retrospectively analyzed.Patients were categorized into groups based on tumor size:small(≤15 mm),medium(16-30 mm),and large(＞30 mm),determined by the maximum tumor diameter on contrast-enhanced MRI scans.Results:PTA results indicated hearing loss in 73 ca-ses(90.1％);vestibular function tests revealed abnormal rates for the anterior semicircular canal,horizontal semi-circular canal,posterior semicircular canal,utricle,and saccule at 29.6％,77.8％,54.3％,90.1％,and 92.6％,respectively.Statistically,no significant differences were found in preoperative hearing test results among patients in different groups(F=0.393,P=0.676).However,significant differences were observed in horizontal semicircular canal gain(r=-0.248,P=0.025),abnormal rates of horizontal semicircular canal catch-up sac-cades(r=0.507,P＜0.001),as well as cVEMP(x2=15.111,P=0.004)and oVEMP thresholds(x2=18.948,P＜0.001)across varying tumor size groups.Conclusion:The extent of hearing loss in patients with vestibular schwannoma is not correlated with tumor size,whereas the degree of vestibular dysfunction demonstrates a corre-lation with tumor size.
acoustic neuromavideo head impulse testvestibular evoked myogenic potential
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