Research advances in the immunomodulatory mechanism of galectin-9 and its role in liver diseases
Galectin-9(Gal-9)is a member of the galectin family that can specifically recognize and bind to galactosides.Recent studies have shown that Gal-9 is highly expressed in the liver and can help to maintain intrahepatic immune homeostasis and perform biological functions in various liver diseases.This article reviews the immunomodulatory functions of Gal-9 and its role in different liver diseases.Studies have shown that Gal-9 has important biological functions in different liver diseases through multiple pathways.Research on the specific immunomodulatory mechanisms and functions of Gal-9 may help to discover the therapeutic role of Gal-9 in liver diseases.