Pathogenesis of liver injury caused by antiviral drugs for coronavirus disease 2019
Drug-induced liver injury is caused by the drug itself and/or its metabolites during drug use or occurs due to hypersensitivity or reduced tolerance to the drug in a particular body type.In the last three years of the diagnosis and treatment of coronavirus disease 2019(COVID-19),antiviral drugs have played a very important role,but there are many reports on liver injury caused by anti-COVID-19 drugs in China and globally,with unknown pathogenesis of liver injury caused by such drugs.This article reviews the research advances in the types of antiviral drugs for COVID-19 and their mechanism in inducing liver injury,in order to promote the rational use of antiviral drugs.
Chemical and Drug Induced Liver InjurySARS-CoV-2Pathologic Processes
万方数据
维普
