CC亚族趋化因子及其受体在慢性肝病中的作用及机制
Role and mechanism of CC chemokines and their receptors in chronic liver diseases
张子欣 1李晖 2王佳慧 3陶雨静 1曾小晏1
作者信息
- 1. 成都中医药大学附属医院中心实验室,成都 610072;成都中医药大学临床医学院,成都 610072
- 2. 成都中医药大学附属医院中心实验室,成都 610072
- 3. 成都中医药大学临床医学院,成都 610072
- 折叠
摘要
近年来,慢性肝病的发病率持续上升,如慢性乙型肝炎、非酒精性脂肪性肝病、肝纤维化、肝硬化、肝细胞癌等,且发病年龄逐渐呈现低龄化趋势.目前许多CC亚族趋化因子在慢性肝病中的作用得到了证实,本文对近年来影响慢性肝病的CC亚家族趋化因子及其受体的研究进展进行总结,探讨其在慢性肝病中的应用潜力,以期为慢性肝病的防治研究提供新思路.
Abstract
In recent years,the incidence rate of chronic liver diseases continues to rise,such as chronic hepatitis B,nonalcoholic fatty liver disease,liver fibrosis,liver cirrhosis,and hepatocellular carcinoma,and the age of onset gradually becomes younger.At present,the role of many CC chemokines in chronic liver diseases has been confirmed.This article summarizes the research advances in CC chemokines and their receptors that affect chronic liver diseases in recent years and explore their potential application in chronic liver diseases,so as to provide new ideas for the prevention and treatment of chronic liver diseases.
关键词
肝疾病/趋化因子类/受体,趋化因子Key words
Liver Diseases/Chemotactic Factors/Receptors,Chemokine引用本文复制引用
基金项目
国家自然科学基金面上项目(82274323)
出版年
2024
国家科技期刊平台
NSTL
万方数据