摘要
高脂血症性急性胰腺炎(HLAP)发病率逐年上升,具有年轻化、病情重、易复发和预后差等特点.复发性HLAP已成为临床亟须解决的难题.本文重点总结了HLAP复发的危险因素以及相应的防治策略.HLAP反复发作的危险因素主要有血脂异常、糖代谢异常、肥胖、吸烟和饮酒等.除了急性期的早期治疗,HLAP还需要长期管理,包括有效地控制血糖和血脂,调节饮食,戒烟限酒.对于不明原因反复发作的HLAP患者,基因检测及基因治疗另辟蹊径,将为此类患者提供新的诊疗策略.
Abstract
The incidence rate of hyperlipidemic acute pancreatitis(HLAP)is gradually increasing,with the features of young age,severe conditions,frequent recurrence,and poor prognosis,and recurrent HLAP has become a difficult issue that needs to be solved urgently in clinical practice.This article summarizes the risk factors for HLAP recurrence and corresponding prevention and treatment strategies.The risk factors for HLAP recurrence include dyslipidemia,abnormal glucose metabolism,obesity,smoking,and drinking.In addition to the early treatment in the acute stage,HLAP requires long-term management,including effective control of blood glucose and lipids,diet regulation,and cigarette and alcohol withdrawal.As for patients with unexplained recurrent HLAP,genetic testing and gene therapy may provide novel diagnosis and treatment strategies.
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