Objective To investigate the clinical effect of repairing fingertip defects with artificial dermis.Methods The 25 patients(30 fingers)with fingertip defects were repaired with artificial dermis.The wound healing,scar formation and sensory function recovery of fingertip were recorded.The recovery of hand function was evaluated ac-cording to the trial standard of upper extremity partial function assessment of hand surgery association of Chinese Med-ical Association,and the subjective satisfaction of patients to postoperative finger was evaluated with Michigan hand outcomes questionnaire.Results All patients were followed up for 3~20 months.All the wounds healed in 4~6(4.7±0.5)weeks.At 3 months after operation,the Vancouver Scar Scale(VSS)was0~4(1.2±1.0)points,there was no obvious scar formation,the two-point discrimination was 4~12(7.5±3.5)mm.The recovery of fingertip sen-sory was as follows:10 fingers were S4 grade,13 fingers were S3+ grade,4 fingers were S3 grade,3 fingers were S2 grade.Three months after operation,the recovery of hand function was excellent in 24 fingers,good in 4 and poor in 2;the patients′subjective satisfaction with their fingers after surgery:19 fingers were very satisfied,9 fingers were satis-fied,and 2 fingers were fair.Conclusions The repair of fingertip defect by artificial dermal is simple,which has good clinical effect,and is especially suitable for primary hospitals.