Objective To compare the efficacy of proximal femoral locking plate and cannulated screw internal fixa-tion for treatment of non-displaced femoral neck fractures in the senile patients.Methods According to different in-ternal fixation,66 senile patients with non-displaced femoral neck fractures were divided into bone plate group(32 ca-ses,proximal femoral locking plate treatment)and screw group(34 cases,cannulated screw treatment).Operation con-ditions,fracture healing time,hip Harris score and postoperative complications were recorded in the two groups.Re-sults Both groups were followed up for 6~95 months.There were no statistical differences in operation time,incision length,intraoperative blood loss and postoperative hemoglobin decline between the two groups(P>0.05).The time of partial weight-bearing in the bone plate group was earlier than the screw group(P<0.05).In the bone plate group,all fractures healed smoothly,and the time was 3.5~8.0(4.63±1.04)months;in the screw group,nonunion occurred in 1 case,and the other 33 cases healed within 3.0~7.5(5.03±1.04)months;there was no statistical difference in fracture healing time between the two groups(P>0.05).Six months after surgery,there was no statistical difference in hip Harris score between the two groups(P>0.05),while the excellent-good rate of hip joint Harris score in the bone plate group was higher than that in the screw group(P<0.05).There was no statistical difference in the incidence rate of postoperative early complications between the two groups(P>0.05),and the incidence rate of medium-long term complications in screw group was higher than that in bone plate group(P<0.05).Conclusions Both proximal femoral locking plate and cannulated screw internal fixation can obtain satisfactory efficacy in the treatment of senile patients with non-displaced femoral neck fractures,compared with cannulated screw,proximal femoral locking plate has better early hip function recovery,and fewer medium-long term complications.