Effect of Shuanghe Zaoren granules on co-morbid negative emotions of chronic sleep disorders
Objective To observe the effect of Shuanghe Zaoren granules on co-morbid negative emotions of chronic sleep disorders.Methods Eighty patients with co-morbid negative emotions of chronic sleep disorders in the outpatient and inpatient clinics of Wuhu Hospital of Traditional Chinese Medicine from January to December 2020 were selected,and they were divided into the observation group and the control group by using the random number table method,40 cases in each group.The control group was treated with Shugan Jieyu capsule,and the observation group was treated with Shuanghe Zaoren granules on the basis of the control group,and both groups were intervened for 3 weeks.The PSQI scores,HAMA scores,TCM syndrome scores before and after the intervention,and the clinical cure rate and safety were compared between the two groups.Results After 3 weeks of intervention,the PSQI scores and total scores of the two groups were lower than those before intervention,and sleep quality,sleep onset latency,total sleep duration,sleep efficiency,daytime functioning scores and total PSQI scores of the observation group were lower than those of the control group(P＜0.01),and the difference between the sleep disorders of the two groups compared with the scores of hypnotic drugs was not statistically significant(P＞0.05).The scores of somatic anxiety factor,mental anxiety factor and total HAMA score of the two groups were lower than that before intervention,and the observation group was lower than that of the control group(P＜0.01).TCM syndrome scores in the two groups were lower than those before the intervention,and the points and total scores of the observation group were lower than those of the control group in terms of difficulty in falling asleep,easy to wake up from sleep,difficult to fall asleep after waking up,sleeplessness throughout the night,impatience and irritability,dizziness and head distension(P＜0.05 or P＜0.01),and the difference between the points of red eyes and tinnitus,dry and bitter mouth,dreaminess,tongue coating,and pulse was not statistically significant when comparing the points of the two groups(P＞0.05).Used the PSQI score as the criterion,after 3 weeks of intervention,the clinical cure rate of the observation group was 37.50％,and the clinical cure rate of the control group was 20.00％,and the difference between two groups was not statistically significant(x2=2.990,P=0.084).Used the HAMA score as the criterion,after 3 weeks of intervention,the clinical cure rate of the observation group was 95.00％,which was higher than that of the control group,which was 50.00％(x2=20.313,P＜0.001).During the intervention process,no abnormality was observed in the blood,urine and stool routine,electrocardiogram and liver and kidney functions of the patients in the two groups.Conclusion Shuanghe Zaoren granules Intervene in patients with chronic sleep disorders patients with co-morbid negative emotions can shorten sleep onset latency,improve sleep efficiency and quality,improve negative emotions,increase clinical cure rate,and have higher safety.
万方数据
维普
