Efficacy of combined vibration-assisted sputum excretion and acetylcysteine nebulization in the treatment of infant pneumonia
Objective To investigate the clinical efficacy of vibration-assisted sputum excretion combined with acetyl-cysteine nebulization in infants with pneumonia.Methods Eighty pediatric patients with pneumonia admitted to Pingxiang Maternal and Child Care from August 2021 to August 2022 were randomly divided into observation group(n=40)and control group(n=40)using a random number table.The control group received standard care plus acetylcysteine solution for inhala-tion,while the observation group received vibration-assisted sputum excretion in addition to the control group treatment.Both groups were treated for 7 days.The study compared the clinical efficacy,time to resolution of symptoms(fever,cough,wheez-ing,crackles),length of hospital stay,hospitalization costs,changes in blood routine indicators(WBC,CRP,PCT)before and after treatment,and adverse events between the two groups.Results The overall effective rate was significantly higher in the observation group(97.50%)compared to the control group(85.00%)(χ2=3.914,P=0.048).The observation group showed shorter durations of fever,cough,wheezing,crackles,as well as a shorter length of hospital stay and lower hospitaliza-tion costs compared to the control group(all P<0.01).After7 days of treatment,both groups showed significant decreases in WBC,CRP,PCT levels compared to baseline,with the observation group showing a more pronounced decrease(P<0.01).There was no significant difference in the overall incidence of adverse events between the observation group(12.50%)and the control group(10.00%)(χ2=0.125,P=0.723).Conclusion The combined use of vibration-assisted sputum excretion and acetylcysteine nebulization showed superior clinical outcomes in treating infant pneumonia,effectively reducing symptoms and inflammation,while maintaining a high safety profile.
万方数据
维普
