Study on the relationship between the quick sequential organ failure assessment score combined with oxygenation index and the severity of patients with emergency critical
Study on the relationship between the quick sequential organ failure assessment score combined with oxygenation index and the severity of patients with emergency critical
Objective To investigate the relationship between the quick sequential organ failure assessment(qSOFA)score combined with oxygenation index(OI)and the severity of patients with emergency critical.Methods A total of 176 patients with emergency criticaladmit-ted to the Seventh People's Hospital of Hebei Province from January 2020 to October 2021 were selected as the study subjects,including 92 patients with sepsis and 84 patients with community-acquired pneumonia.According to the results of acute physiology and chronic health status evaluation Ⅱ(APACHE Ⅱ)score within 24 hours after admission,the selected patients were divided into the mild group(15 points≤APACHE Ⅱ score<20 points,n=58),the moderate group(20 points ≤APACHE Ⅱ score<30 points,n=70),and the severe group(APACHE Ⅱ score ≥30 points,n=48).The the blood gas index[partial pressure of carbon dioxide(PaCO2),arterial oxygen(PaO2),OI],and qSOFA score of three groups of patients were collected and compared.The correlation between blood gas index and qSOFA score were analyzed using Pearson correla-tion,the factors affecting the severity of patients with emergency critical were analyzed using ordered multi-classification Logistic regression.The value of the qSOFA score combined with OI in predicting the severity of patients with emergency critical was analyzed by the receiver operating characteristic(ROC)curve.Results PaCO2 and qSOFA score in the severe group were higher than those in the moderate and the mild groups,and PaCO2 and qSOFA score in the moderate group were higher than those in the mild group,the differences were statistically significant(P<0.05).However,PaO2 and OI in the three groups showed a downward trend,the severe group was lower than the moderate group and the mild group,and the moderate group was lower than the mild group,the differences were statistically significant(P<0.05).Pearson correlation analy-sis showed that PaCO2 was positively correlated with qSOFA score(r=0.238,P<0.001).PaO2 and OI were negatively correlated with qSOFA score(r=-0.197,-0.328,P<0.05).Multivariate Logistic regression analysis showed that the higher PaCO2 and qSOFA score,the more severe the emergency critically ill patients were.However,the lower PaO2 and OI,the more serious the emergency critically ill patients were.ROC curve analysis showed that the maximum area under the curve(AUC)of qSOFA score combined with OI in predicting the severity of patients with emergency critical was 0.895,which was greater than that of each individual index and other combined indexes(P<0.05).Conclusion qSO-FA score and OI were related to the severity of patients with emergency critical.The combination of the two was more valuable in predicting the se-verity of patients with emergency critical.It could be used as auxiliary indicators for clinical diagnosis and evaluation severity of patients with emer-gency critical.
关键词
急诊/危重症/危重程度/快速序贯器官功能衰竭评估评分/氧合指数
Key words
Emergency/Critical/Severity/Quick sequential organ failure assessment score/Oxygenation index