Objective To develop and validate a lung ultrasound(LUS)-acute respiratory distress syndrome(ARDS)score model for di-agnosis of ARDS and compare its performance with that of chest CT.Methods A total of 325 patients who received invasive ventilator treatment in the emergency department or ICU of Ma'anshan People's Hospital from March 2019 to March 2023 were included in this retrospective study,and then were divided into the training set 243 cases and the validation set 82 cases at a ratio of 3∶1.With the diagnosis results of the expert team as the"reference",the patients were divided into the ARDS group(63 cases in the training set,37 cases in the validation set)and the non ARDS group(180 cases in the training set,45 cases in the validation set).All patients received LUS examination and the examination method was the lung 12 partition method,and then the Logistic regression model was used to build the LUS-ARDS scoring system.The diagnostic efficacy of LUS-ARDS score on ARDS using ROC was analyzed,and then obtain diagnostic cutoff values,and calculate the area under the curve(AUC).Results 233 cases(26.03％)ARDS and 82 cases(45.12％)ARDS were included in the training and validation sets,respectively.LUS-ARDS score was constructed by the left and right LUS aeration scores and anterolateral pleural line abnormalities,LUS-ARDS score=2.6 x left LUS aeration score+1 × right LUS aeration score+3.4 × no.of anterolateral regions with an abnormalpleural line.LUS-ARDS score had an area under the receiver operating characteristic(ROC)curve of 0.90(95％CI:0.85-0.95)in the training set,and 0.85(95％CI:0.77-0.93).In patients with chest CT,the AUC of the LUS-ARDS score ROC was 0.85(95％CI:0.78-0.90).Conclusion The LUS-ARDS score can be used for accurate diagnosis of ARDS,and it may be a useful auxiliary tool for diagnosing ARDS.Its diagnostic performance is compa-rable to that of chest CT(gold standard).
维普
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