Objective To study the effect of non-stop aspirin in the perioperative period of shoulder arthroscopy on the difficulty of sur-gery during the procedure and postoperative joint pain and function.Methods A total of 177 patients who underwent shoulder arthroscopic surgery at the Department of Orthopedics,Beijing Friendship Hospital,Capital Medical University from August 2019 to August 2022 were retrospectively selected as the study subjects.And they were divide into observation group(n=37)and control group(n=140)based on whether aspirin has been discontinued or not.The observation group did not stop taking aspirin during the perioperative period,the control group did not take aspirin in the past.The operation time,anaesthesia time,blood loss,Constant score before and 6 months after surgery,visual analogue score(VAS),cardiovascular and cerebrovascular complications,non-cardiovascular and cerebrovascular complications in the two groups of patients were com-pared.Results Successful completion of surgery and 6-month follow-up data were obtained in two groups.There were no statistically signifi-cant differences on operation time,anaesthesia time,blood loss,preoperative and 6-month postoperative Constant scores and VAS scores between the two groups(P>0.05).No cardiovascular and cerebrovascular complications occurred in the patients of the observation group in the 6 months after surgery,and one case of acute cerebral infarction occurred in the control group.There were 2 cases of shoulder joint stiffness and no wound infection in the patients of the observation group after surgery,and 13 cases of shoulder joint stiffness and 1 case of wound infection in the control group.There was no statistically significant difference in the incidence of complications between the two groups(P>0.05).Conclusion Non-stop aspirin use during the perioperative period of shoulder arthroscopy does not increase operative time,anaesthesia time,blood loss or complica-tion rate,does not increase the difficulty of the operation and does not affect the postoperative recovery outcome.