临床和实验医学杂志2024,Vol.23Issue(5) :558-561.DOI:10.3969/j.issn.1671-4695.2024.05.029

喉罩全身麻醉联合腋路臂丛神经阻滞对肱骨近端骨软骨瘤手术患者血流动力学及应激反应的影响

Effect of laryngeal mask general anesthesia combined with axillary brachial plexus block on hemodynamics and stress response in pa-tients undergoing surgery for osteochondroma of proximal humerus

李晓欣 段志祥 邵甜 卢玉蓉
临床和实验医学杂志2024,Vol.23Issue(5) :558-561.DOI:10.3969/j.issn.1671-4695.2024.05.029

喉罩全身麻醉联合腋路臂丛神经阻滞对肱骨近端骨软骨瘤手术患者血流动力学及应激反应的影响

Effect of laryngeal mask general anesthesia combined with axillary brachial plexus block on hemodynamics and stress response in pa-tients undergoing surgery for osteochondroma of proximal humerus

李晓欣 1段志祥 1邵甜 1卢玉蓉1
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作者信息

  • 1. 运城市中心医院麻醉科 山西 运城 044000
  • 折叠

摘要

目的 探讨喉罩全身麻醉联合腋路臂丛神经阻滞对肱骨近端骨软骨瘤手术患者血流动力学、应激反应的影响.方法 回顾性选取2017年1月至2022年11月在运城市中心医院行手术治疗的80例肱骨近端骨软骨瘤患者作为研究对象.按接受麻醉方案的不同将患者分为观察组和对照组,每组各40例.观察组术中采用喉罩联合腋路臂丛神经阻滞,对照组术中采用喉罩全身麻醉.观察并记录两组患者麻醉前(t0)、置入喉罩时(t1)及拔除喉罩时(t2)平均动脉压(MAP)及心率,统计两组患者苏醒时间及术后6、12和24 h的疼痛程度[视觉模拟评分法(VAS)评分],比较两组患者术前、术后4和12 h的应激反应指标[去甲肾上腺素(NE)、血管紧张素Ⅱ(AngⅡ)、丙二醛、超氧化物歧化酶(SOD)]水平,统计麻醉恢复室中的并发症情况.结果 t.时,两组患者MAP及心率比较,差异均无统计学意义(P>0.05);t1、t2时,观察组患者 MAP 分别为(94.53±8.11)、(92.63±6.10)mmHg,心率分别为(119.35±10.18)、(120.41±9.55)次/min,均低于对照组[MAP:(113.71±8.45)、(116.55±8.66)mmHg;心率:(135.79±11.85)、(138.35±10.96)次/min],差异均有统计学意义(P<0.05).观察组苏醒时间为(5.71±1.45)min,短于对照组[(10.93±2.21)min],差异有统计学意义(P<0.05).两组术后4、12、24 h VAS评分均逐渐降低,差异均有统计学意义(P<0.05),但组间比较差异均无统计学意义(P>0.05).术后4、12 h,观察组NE、AngⅡ、丙二醛水平均显著低于对照组,SOD水平明显高于对照组,差异均有统计学意义(P<0.05).观察组并发症发生率为10.00%,稍低于对照组(27.50%),但两组比较,差异无统计学意义(P>0.05).结论 喉罩全身麻醉联合腋路臂丛神经阻滞应用于肱骨近端骨软骨瘤手术患者能有效维持稳定的血流动力学状态,缩短苏醒时间,减轻术后疼痛,抑制术后的应激反应,能够兼顾安全性与有效性.

Abstract

Objective To investigate the effects of laryngeal mask anesthesia combined with axillary brachial plexus block on hemodynam-ics and stress response in patients undergoing surgery for osteochondroma of proximal humerus.Methods Eighty patients with proximal humeral osteochondroma who underwent surgical treatment at Yuncheng Central Hospital from January 2017 to November 2022 were retrospectively selected as the study subjects,and they were divided into the observation group and the control group according to different anesthesia methods,with 40 ca-ses in each group.The observation group was treated with laryngeal mask general anesthesia combined with axillary brachial plexus block,and the control group was treated with laryngeal mask general anesthesia.The mean arterial pressure(MAP)and heart rate of two groups of patients were observed and recorded before anesthesia(t0),during the insertion of laryngeal mask(t1),and during the removal of laryngeal mask(t2).The recovery time,postoperative pain[visual analog scale(VAS)score]levels at 6,12,and 24 hours after surgery of two groups of patients were sta-tistically analyzed.The levels of stress response indicators[(norepinephrine(NE),angiotensin Ⅱ(Ang Ⅱ),malondialdehyde]were compared between two groups of patients before surgery and 4 and 12 hours after surgery.Results At t0,there was no statistically significant difference in MAP and heart rate between the two groups of patients(P>0.05);at t1 and t2,the MAP of the observation group patients were(94.53± 8.11),(92.63±6.10)mmHg,and the heart rates were(119.35±10.18)and(120.41±9.55)beats/min,respectively,which were lower than those of the control group[MAP:(113.71±8.45)and(116.55±8.66)mmHg;heart rates:(135.79±11.85)and(138.35±10.96)beats/min],and the differences were statistically significant(P<0.05).The awakening time of the observation group was(5.71±1.45)mi-nutes,which was shorter than that of the control group[(10.93±2.21)minutes],and the difference was statistically significant(P<0.05).The VAS scores of the two groups gradually decreased at 4,12,and 24 hours after surgery,and the differences were statistically significant(P<0.05),but there was no statistically significant difference between the groups(P>0.05).At 4 and 12 hours after surgery,the levels of NE,Ang Ⅱ,and malondialdehyde in the observation group were significantly lower than those in the control group,and the differences were statistically significant(P<0.05).The incidence of complications in the observation group was 10.00%,which was slightly lower than that in the control group(27.50%),but there was no statistically significant difference between the two groups(P>0.05).Conclusion The application of la-ryngeal mask anesthesia combined with axillary brachial plexus block in patients undergoing surgery for proximal humeral osteochondroma can effec-tively maintain a stable hemodynamic state,shorten recovery time,reduce postoperative pain,suppress postoperative stress response,which can be both safe and effective.

关键词

骨软骨瘤/血流动力学/腋路臂丛神经阻滞/喉罩全身麻醉/应激反应

Key words

Osteochondroma/Hemodynamics/Axillary brachial plexus block/Laryngeal mask general anesthesia/Stress response

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基金项目

山西省科技厅重点研发社会发展项目(201903D321161)

出版年

2024
临床和实验医学杂志
首都医科大学附属北京友谊医院

临床和实验医学杂志

CSTPCD
影响因子:1.504
ISSN:1671-4695
参考文献量17
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