Effect of laryngeal mask general anesthesia combined with axillary brachial plexus block on hemodynamics and stress response in pa-tients undergoing surgery for osteochondroma of proximal humerus
Effect of laryngeal mask general anesthesia combined with axillary brachial plexus block on hemodynamics and stress response in pa-tients undergoing surgery for osteochondroma of proximal humerus
Objective To investigate the effects of laryngeal mask anesthesia combined with axillary brachial plexus block on hemodynam-ics and stress response in patients undergoing surgery for osteochondroma of proximal humerus.Methods Eighty patients with proximal humeral osteochondroma who underwent surgical treatment at Yuncheng Central Hospital from January 2017 to November 2022 were retrospectively selected as the study subjects,and they were divided into the observation group and the control group according to different anesthesia methods,with 40 ca-ses in each group.The observation group was treated with laryngeal mask general anesthesia combined with axillary brachial plexus block,and the control group was treated with laryngeal mask general anesthesia.The mean arterial pressure(MAP)and heart rate of two groups of patients were observed and recorded before anesthesia(t0),during the insertion of laryngeal mask(t1),and during the removal of laryngeal mask(t2).The recovery time,postoperative pain[visual analog scale(VAS)score]levels at 6,12,and 24 hours after surgery of two groups of patients were sta-tistically analyzed.The levels of stress response indicators[(norepinephrine(NE),angiotensin Ⅱ(Ang Ⅱ),malondialdehyde]were compared between two groups of patients before surgery and 4 and 12 hours after surgery.Results At t0,there was no statistically significant difference in MAP and heart rate between the two groups of patients(P>0.05);at t1 and t2,the MAP of the observation group patients were(94.53± 8.11),(92.63±6.10)mmHg,and the heart rates were(119.35±10.18)and(120.41±9.55)beats/min,respectively,which were lower than those of the control group[MAP:(113.71±8.45)and(116.55±8.66)mmHg;heart rates:(135.79±11.85)and(138.35±10.96)beats/min],and the differences were statistically significant(P<0.05).The awakening time of the observation group was(5.71±1.45)mi-nutes,which was shorter than that of the control group[(10.93±2.21)minutes],and the difference was statistically significant(P<0.05).The VAS scores of the two groups gradually decreased at 4,12,and 24 hours after surgery,and the differences were statistically significant(P<0.05),but there was no statistically significant difference between the groups(P>0.05).At 4 and 12 hours after surgery,the levels of NE,Ang Ⅱ,and malondialdehyde in the observation group were significantly lower than those in the control group,and the differences were statistically significant(P<0.05).The incidence of complications in the observation group was 10.00%,which was slightly lower than that in the control group(27.50%),but there was no statistically significant difference between the two groups(P>0.05).Conclusion The application of la-ryngeal mask anesthesia combined with axillary brachial plexus block in patients undergoing surgery for proximal humeral osteochondroma can effec-tively maintain a stable hemodynamic state,shorten recovery time,reduce postoperative pain,suppress postoperative stress response,which can be both safe and effective.
关键词
骨软骨瘤/血流动力学/腋路臂丛神经阻滞/喉罩全身麻醉/应激反应
Key words
Osteochondroma/Hemodynamics/Axillary brachial plexus block/Laryngeal mask general anesthesia/Stress response