Objective To evaluate the effect and safety of fluid gelatin in unilateral biportal endoscopic for lumbar degenerative diseases.Methods A total of 89 consecutive patients with lumbar degenerative diseases were treated by unilateral biportal endoscopic in Beijing Friendship Hospital,Capital Medical University from January 2020 to June 2022 were etrospcctive analyzed.According to whether fluid gelatin was used dur-ing surgery,the patients were divided into the experimental group(using fluid gelatin,n=40)and the control group(not using fluid gelatin,n=49).The back and leg pain[visual analog scale(VAS)]score,oswestry disabillty index(ODI)before operation,3 days,1 month,and 3 months after operation were compared;the clinical outcomes,postoperative drainage volume and coagulation function,and surgical complications were compared between the two groups.Results At 3 days,1 month,and 3 months after operation,the back and leg VAS scores,and ODI in two groups showed significant improvement compared to before operation,the differences were statistically significant(P＜0.05).However,there were no statistically significant differences in back and leg VAS scores and ODI between the two groups(P＞0.05).The results of Fischgr-und evaluation criteria at 3 month after operation showed that the excellent and good rate was 90.0％in the experimental group and 85.7％in the control group,there was no statistically significant difference(P＞0.05).The postoperative drainage volume in experimental group was(15.23±13.46 mL),which was significantly lower than that in the control group[(28.69±29.68)mL],the difference was statistically significant(P＜0.05).There were no statistically significant differences in coagulation indicators between the two groups before and after operation(P＞0.05).There were 2 cases(5.0％)of complications in the experimental group and 2 cases(4.1％)in the control group.There was no statisti-cally significant difference in the incidence of complications between the two groups(P＞0.05).Conclusion The application of fluid gelatin in unilateral biportal endoscopic for lumbar degenerative diseases has definite clinical efficacy,can significantly reduce postoperative drainage vol-ume,and does not affect coagulation function,does not increase the incidence of complications,and the safety is relatively high.
维普
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