Study on the safety of carbohydrates-based nutritional liquid for pre-operation use in surgical anesthesia of elderly patients with inter-trochanteric fracture
Study on the safety of carbohydrates-based nutritional liquid for pre-operation use in surgical anesthesia of elderly patients with inter-trochanteric fracture
Objective To observe the safety of carbohydrates-based nutritional liquid for pre-operation use in surgical anesthesia of elderly patients with intertrochanteric fracture.Methods A total of 48 patients with intertrochanteric fractures admitted to Gaochun Hospital Affil-iated to Jiangsu University from April 2022 to May 2023 were prospectively selected as the study subjects.They were divided into the intervention group(n=24)and the control group(n=24)according to random number table method.The patients in the intervention group were fasting from solid food for 8 hours before surgery,but drank 200 mL of carbohydrates-based nutritional liquid(special medical carbohydrate component formula with a carbohydrate content of 12.5％)for pre-operation use 2 hours before surgery;the patients in the control group were fasting and drinking-free for 8 hours before surgery.The subjective states before and after surgery,gastric emptying status,intraoperative anesthesia indica-tors(anesthesia time and blood gas status),the levels of fasting blood glucose,insulin,and insulin resistance index at admission and during sur-gery two groups were recorded.Results Before surgery,the proportion of thirsty patients in the intervention group was 0,which was significantly lower than that in the control group(54.2％),and the difference was statistically significant(P＜0.05);there were no statistically significant differences in the proportion of patients with palpitations,fear,hunger,muscle tremors,and dizziness between the two groups(P＞0.05).The residual volume of the intervention group before surgery was(0.23±0.08)mL,which was lower than that of the control group[(0.38±0.11)mL],the blood levels of pH,PaCO2,HCO3-were 7.38±0.04,(43.30±2.35)mmHg,and(24.63±0.52)mmol/L,respectively,which were higher than those in the control group[7.34±0.03,(41.62±2.81)mmHg,and(23.70±1.41)mmol/L],and the differences were sta-tistically significant(P＜0.05).The insulin resistance index of the intervention group patients at admission was 1.94(1.4,4.9),which was higher than that of the control group[0.66(0.3,1.8)],the difference in insulin resistance index between admission and surgery was 1.19(0.1,3.4),which was higher than that of the control group[-0.23(-0.6,1.0)],and the difference was statistically significant(P＜0.05);there were no statistically significant differences in blood glucose and serum insulin between the two groups at admission and during surgery(P＞0.05).Conclusion It is high safe during the anesthesia for the elderly patients with intertrochanteric fracture surgery to drink 200 mL of carbo-hydrates-based nutritional liquid for pre-operation use 2 hours during the before surgery.
维普
万方数据