Preparation and Bioactivities of Lignin-based Polyphenols
Aiming at the problems of low active sites and poor activity of lignin,pyrogallol modified enzymatic hydrolyzed lignin(PEHL),a lignin-based polyphenol compound,was prepared by one-pot demethylation and phenolic modification from acidic molten salt hydrate.The experimental results demonstrated a significant increase in the reaction sites of demethylated enzymatic hydrolyzed lignin(DEHL)and PEHL,with phenolic hydroxyl groups increasing from 1.25 mmol/g in raw enzymatic hydrolyzed lignin(EHL)to 3.49 and 5.70 mmol/g,respectively.Furthermore,DPPH·scavenging experiments revealed a significant enhancement in the antioxidant activities of lignin-based polyphenol compounds,and the DPPH·scavenging rates of DEHL and PEHL increased by 46.9％and 64.4％,respectively.Moreover,PEHL showed promising antibacterial activity,and low cytotoxicity with inhibition rates of E.coli and S.aureus by 85.22％and 99.76％,respectively.
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