Research Progress on the Application of Lignin and Its Derivatives in the Pharmaceutical Industry
Lignin had good biocompatibility,chemical stability,and processability,demonstrating a wide range of potential applications in biomedical and tissue engineering fields.On the basis of a brief introduction to the structure of lignin,this paper reviewed the research progress of lignin as a new type of loading material in the pharmaceutical industry,such as drug carriers and sustained-release systems,medical auxiliary materials,and pharmaceutical biosensors.The pharmacological activities of lignin in antiviral,anti-tumor,blood glucose and lipid regulation,as well as anti-inflammatory,anticoagulant,and skincare were introduced.The application of lignin degradation products such as vanillin and its derivatives,catechol and phenol were summerized.Finally,the problems and future directions in the application of lignin and its derivatives in the pharmaceutical industry were analyzed,aiming to promote the transformation of lignin from industrial waste to high value-added pharmaceutical applications,in order to achieve its wider application in the pharmaceutical field.