Analysis of the relationship between thyroid and adrenal endocrine metabolism,impulse control,and ex-otic behavior attack in patients with bipolar disorder and exploration of early detection value
Objective:To study the relationship between thyroid and adrenal endocrine metabolism,im-pulse control,and overt behavioral aggression in patients with bipolar disorder(BD),and to explore its early de-tection value.Method:A total of 98 first-time BD patients were retrospectively selected as the observation group.They were divided into impulsive aggressive behavior group(n =43)and non impulsive aggressive be-havior group(n =55)based on their presence and absence of impulsive aggressive behavior.Detect the levels of thyroid and adrenal endocrine metabolism in all subjects,and use Spearman correlation analysis to examine the correlation between endocrine metabolism and impulsive aggressive behavior in BD patients.Results:Cortisol(Cor),triiodothyronine(FT3),and thyroid stimulating hormone(TSH)in the observation group were all higher than those in the control group,while adrenocorticotropic hormone(ACTH)and thyroid hormone(T4)were significantly lower than those in the control group(all P＜0.05).The Cor,FT3,and TSH of the impulsive ag-gressive behavior group were significantly higher than those of the non impulsive aggressive behavior group,while ACTH and T4 were significantly lower than those of the non impulsive aggressive behavior group(all P＜0.05).Abnormal expression of Cor,ACTH,FT3,TSH,and T4 are all influencing factors for impulsive aggressive behavior in BD patients.Conclusion:Abnormalities in thyroid and adrenal endocrine metabolism are influen-cing factors for impulsive overtones and aggressive behavior in BD patients,and they are correlated with BD ag-gressive behavior,which may have early detection value.
bipolar disorderThyroid and adrenal endocrine metabolismBehavioral attacksTes-ting value
万方数据
维普
