Review and new progress of the efficacy and safety of light therapy for bipolar depression
Bipolar Disorder(BD)is a chronic and recurrent disorder,and the treatment for bipolar depres-sion is limited.Studies have found that light therapy(LT),which is effective in the treatment of seasonal affec-tive disorder(SAD),can also be used to treat bipolar depression.LT exerts an antidepressant effect by improving BD circadian rhythm disorders and regulating monoamine neurotransmitters.LT is relatively safe and effective as an adjunctive therapy for bipolar depression.At present,more standardized RCTs with larger sample sizes and longer intervention and follow-up periods are needed to provide strong evidence for LT treatment of bipolar de-pression.