摘要
目的:探索强迫症(OCD)患者心理社会功能的损伤及影响因素.方法:研究纳入2021 年4 月至2022 年6 月在南京脑科医院门诊就诊的OCD患者 153 例,使用耶鲁布朗强迫量表(Y-BOCS)评估强迫症严重程度,强迫症症状分类量表修订版(OCI-R)、贝克焦虑量表(BAI)、贝克抑郁量表(BDI-Ⅱ)、席汉残疾量表(SDS)、心理社会功能问卷评估强迫维度、情绪状态和心理社会功能;采用独立样本t检验、相关分析、多元回归分析探索心理社会功能的影响因素.结果:强迫症患者Y-BOCS、OCI-R强迫思维维度、BAI、BDI-Ⅱ、SDS与心理社会功能存在正相关(r = 0.381、0.276、0.221、0.549、0.417,P均＜0.05).多元回归结果显示心理社会功能总分受强迫行为和BDI-Ⅱ影响显著(β=0.151、0.492,P均＜0.05);主观幸福感受BDI-Ⅱ和SDS工作/学习维度影响显著(β=0.365、0.225,P均＜0.05);心理认知受BDI-Ⅱ影响显著(β=0.510,P＜0.05);社会功能受BDI-Ⅱ影响显著(β=0.478,P＜0.05).结论:不同临床特征下强迫症患者的心理社会功能损害不同,抑郁症状是心理社会功能的重要影响因素.
Abstract
Objective:To explore the impairment and influencing factors of psychosocial functioning in patients with obsessive-compulsive disorder(OCD).Method:A cross-sectional study was conducted in 153 OCD patients who visited the outpatient clinic of Brain Hospital Affiliated to Nanjing Medical University from A-pril 2021 to June 2022.The severity of OCD was assessed using the Yale-Brown obsessive compulsive Scale(Y-BOCS),obsessive-compulsive inventory-revised(OCI-R),Beck anxiety inventory(BAI),Beck depression in-ventory-Ⅱ(BDI-Ⅱ),Sheehan disability scale(SDS),and psychosocial functioning questionnaire were used to assess obsessive-compulsive dimension,mood,and psychosocial functioning.Independent-samples T-test and correlation analysis were used to explore the influencing factors of psychosocial functioning,and then the differ-ence factors were included in multiple regression analysis for further discussion.Results:The score of Y-BOCS,BAI,BDI-Ⅱand SDS were positively correlated with psychosocial functioning(r =0.381,0.276,0.221,0.549,0.417,all P＜0.05).Multiple regression analysis showed that the total score of psychosocial functioning was significantly affected by compulsive behavior and BDI(β =0.151,0.492,all P＜0.05).Subjective well-be-ing was significantly affected by BDI-Ⅱ and work/study dimension(SDS)(β=0.365,0.225,all P＜0.05).The psychological cognitive dimension was significantly affected by BDI-Ⅱ(β =0.510,P＜0.05).The social functioning dimension was significantly affected by BDI-Ⅱ(β =0.478,P＜0.05).Conclusion:OCD pa-tients with different clinical characteristics have different psychosocial functioning impairment,and depressive symptoms are an important influencing factor of psychosocial functioning.
基金项目
国家自然科学基金青年基金(81901390)
江苏省社会发展重点研发计划专项(BE2021616)
江苏省社会发展面上项目(BE2022678)
南京市医学科技发展重点项目(ZKX20029)
南京医科大学强迫症专病队列研究项目(NMUC2020034)
NETL
NSTL
万方数据