Advances in the genetic characterization of childhood-onset schizophrenia
This article summarized the genetic characteristics of childhood onset schizophrenia(COS).The heritability of COS was over 80%,which showed that①relevant risk genes overlaps with adult schizophrenia.②Many risk genes are also associated with earlier neurodevelopmental disorders such as autism spectrum disorder;③The risk gene structure of COS contains more common and rare variants,including copy number variants.
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