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老年抑郁症患者治疗依从性的影响因素

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目的:探讨老年抑郁症患者治疗依从性现状,并分析相关影响因素.方法:纳入2020年2月至2022年8月收治入我院的156例老年抑郁患者作为研究对象,采用药物依从性评定量表(medication adherence rating scale,MARS)评估治疗依从性,并以其评分中位数为界限分为依从性高组与依从性低组各78例.对比组间患者一般资料、临床资料、睡眠质量、服药态度以及抑郁程度,并运用多因素Logistic回归模型对影响患者治疗依从性的相关因素进行分析.结果:156例老年抑郁患者MARS评分为(4.42±1.85)分,中位数值为5分.依从性高组患者具有家族史、文化程度(大专及以上)及婚姻状态(已婚)占比均高于依从性低组,匹兹堡睡眠质量指数(Pittsburgh sleep quality index,PSQI)及贝克抑郁量表(Beck depression inventory,BDI)得分均低于依从性低组(P均<0.05).多因素Logistic回归分析结果显示家族史、文化程度、婚姻状态和PSQI及BDI得分均是患者服药依从性的影响因素(P均<0.05).结论:老年抑郁症患者治疗依从性处于低等水平,文化程度、婚姻状态是老年抑郁症患者的独立保护因素,家族史、PSQI及BDI得分是其独立危险因素.
Influencing factors of treatment compliance of elderly patients with depression
Objective:To explore the status quo of treatment compliance of elderly patients with depression and analyze relevant influencing factors.Method:156 elderly depression patients admitted to our hospital from February 2020 to August 2022 were included as the study subjects.The treatment compliance was assessed by the medication adherence rating scale(MARS),and divided into the high compliance group and the low compliance group with the median score as the boundary,78 cases each.The general data,clinical data,sleep quality,medication attitude and depression degree of patients between the two groups were compared,and the related factors affecting the treatment compliance of patients were analyzed using multivariate logistic regression model.Results:The scale of MARS of 156 elderly patients with depression was(4.42±1.85),and the median value was 5,which was at a low compliance level.The proportion of patients with family history,education level(junior college or above)and marital status(married)in the high compliance group was higher than that in the low compliance group,and the scores of Pittsburgh sleep quality index(PSQI)and Beck depression inventory(BDI)were lower than those in the low compliance group(all P<0.05).Multivariate Logistic regression analysis showed that family history,education level,marital status,PSQI and BDI scores were the influencing factors of patients'drug compliance(all P<0.05).Conclusion:The treatment compliance of elderly patients with depression is at a low level.Education level and marital status are independent protective factors for elderly patients with depression,and family history,PSQI and BDI scores are independent risk factors.

depressioncompliancesleep qualityBecker depression scaledrug attitude scale

许冬琴、严焕然、潘友让

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312000 绍兴市第七人民医院

抑郁症 依从性 睡眠质量 贝克抑郁量表 药物态度量表

浙江省医药卫生科技计划项目

2023RC292

2024

临床精神医学杂志
南京医科大学附属脑科医院

临床精神医学杂志

CSTPCD
影响因子:1.108
ISSN:1005-3220
年,卷(期):2024.34(4)