首页|癫痫患者并发注意缺陷多动障碍风险预警模型构建与验证

癫痫患者并发注意缺陷多动障碍风险预警模型构建与验证

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目的:探讨癫痫患者并发注意缺陷多动障碍(attention deficit hyperactivity disorder,ADHD)的危险因素,建立风险预警模型并进行验证.方法:选取2020年1月至2023年5月绍兴市第七人民医院120例癫痫患者,根据患者是否并发ADHD分为ADHD组和无ADHD组,对相关的临床特征进行Logistic回归分析,构建风险预警模型.结果:本研究共有120例癫痫患者,有38例患者共患ADHD,并发率为31.67%.Logistic回归分析结果显示,症状性癫痫(OR=7.116)、多病灶放电(OR=11.386)、病程>10年(OR=10.130)、首次发病年龄≤5岁(OR=9.116)和MRI脑部异常(OR=4.837)和联合用药(OR=6.257)是癫痫患者并发ADHD的独立危险因素(P<0.05).模型回归方程Logit(P)=1.962 ×症状性+2.432 ×多病灶放电+2.316×病程(>10年)+2.210×首次发病年龄(≤5岁)+1.576 ×MRI脑部异常+1.834 ×联合用药-5.474.结论:癫痫患者并发ADHD受病症特征、发病年龄及家庭等因素影响,以此建立的风险预警模型具有较好的预测效能.
Construction and verification of risk early warning model for epilepsy patients complicated with attention deficit hyperactivity disorder
Objective:To explore the risk factors of attention deficit hyperactivity disorder(ADHD)in patients with epilepsy,and to establish a risk warning model and verify it.Method:A total of 120 patients with epilepsy in Shaoxing Seventh People s Hospital from January 2020 to May 2023 were selected and divided into the ADHD group and the non-ADHD group according to whether the patients were complicated with ADHD.Logistic regression analysis was performed on the relevant clinical characteristics to construct a risk early warning model.Results:In this study,there were of 120 epilepsy patients,and 38 of them were complicated with ADHD,the complication rate was 31.67%.Logistic regression analysis showed that symptomatic epilepsy(OR=7.116),multifocal discharge(OR=11.386),course of disease>10 years(OR=10.130),age of first onset≤5 years(OR=9.116),MRI brain abnormalities(OR=4.837)and combined medication(OR=6.257)were independent risk factors for ADHD in patients with epilepsy.The model regression equation Logit(P)=1.962 × symptomatic+2.432 × multifocal discharge+2.316 × course of disease(>10 years)+2.210 × age of first onset(≤5 years)+1.576 × MRI brain abnormalities+1.834 × combined medication-5.474.Conclusion:Epilepsy patients with ADHD are affected by disease characteristics,age of onset,family and other factors.The risk early warning model established based on this has good predictive efficacy.

epilepsyattention deficit hyperactivity disorderrisk factorsrisk model

周芬、姚秋女、吕江琴

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312000 浙江省绍兴市第七人民医院

癫痫 注意缺陷多动障碍 危险因素 风险模型

绍兴市科技计划项目

2020A13049

2024

临床精神医学杂志
南京医科大学附属脑科医院

临床精神医学杂志

CSTPCD
影响因子:1.108
ISSN:1005-3220
年,卷(期):2024.34(5)