首页|毒蛇咬伤致皮肤坏死性感染的危险因素及预测模型研究

毒蛇咬伤致皮肤坏死性感染的危险因素及预测模型研究

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目的:分析毒蛇咬伤致皮肤坏死性感染的危险因素,并构建预测模型.方法:回顾性分析99例毒蛇咬伤患者的临床资料,确定是否发生皮肤坏死性感染为结局,采用单因素及多因素logistics回归分析构建预测模型并予以验证.结果:蛇伤严重度评分、血糖及D-二聚体水平为毒蛇咬伤致皮肤坏死性感染的危险因素(均P<0.05).利用上述危险因素构建列线图预测模型,预测发生皮肤坏死性感染的曲线下面积分别为0.92;预测模型的校准曲线在两组中均表现出较好的一致性.结论:蛇伤严重度评分、血糖及D-二聚体水平是毒蛇咬伤后发生皮肤坏死性感染的危险因素,该模型可为临床决策提供参考.
Study on risk factors and prediction model of skin necrotic infection caused by venomous snake bites
Objective:To analyze the risk factors of skin necrotizing infections caused by venomous snake bites and construct a prediction model.Methods:Clinical data of 99 venomous snake bite patients were retrospectively analyzed to determine whether skin necrotizing infection occurred as an outcome,and predictive model was con-structed and validated using unifactorial and multifactorial logistic regression analysis.Results:Snakebite severity score,blood glucose and D-dimer level were the risk factors of skin necrotizing infections caused by venomous snake bites(all P<0.05).The area under the curve for predicting the occurrence of skin necrotizing infections was 0.92 using the above risk factors to construct a column-line graph prediction model;the calibration curves of the prediction model showed good consistency in both groups.Conclusion:Snakebite severity score,blood glucose and D-dimer levels are risk factors for the occurrence of skin necrotizing infection after venomous snake bites,and the model can provide a reference for clinical decision-making.

venomous snake bitenecrotizing infectionrisk factorprediction model

郝嘉宁、王宇宏、王文博、戴秋婷、朱明月、李伦超、赵晓东、刘双庆

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解放军总医院第四医学中心急诊医学科(北京,100037)

联勤保障部队天津康复疗养中心内分泌科

三峡大学第二临床附属医院心内科

毒蛇咬伤 坏死性感染 危险因素 预测模型

2024

临床急诊杂志
华中科技大学同济医学院

临床急诊杂志

CSTPCD
影响因子:0.652
ISSN:1009-5918
年,卷(期):2024.25(3)
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