Analysis of clinical characteristics and factors related to long-term hospitalization in adult patients bitten by vipers
Objective:To analyze the clinical characteristics of adult patients bitten by vipers in the Hubei area and the factors related to long-term hospitalization,establish a predictive model,and provide clinical reference for the diagnosis and treatment of snakebite injuries.Methods:A retrospective analysis of the clinical data of 32 adult patients bitten by vipers,who were admitted to our hospital's emergency department from April 2018 to June 2023,was conducted to assess baseline levels.Based on the length of hospital stay,patients were divided into a short-term hospitalization group(17 cases)and a long-term hospitalization group(15 cases).Univariate analysis and multivariate logistic regression were performed between groups to establish a Nomogram model,and data vali-dation was refined with ROC curves,among other methods.Results:Patients in the long-term hospitalization group had higher baseline levels upon admission,including systolic blood pressure,red blood cell count,white blood cell count,neutrophil count,levels of alanine aminotransferase,and activated partial thromboplastin time,compared to the short-term hospitalization group(P＜0.05).Multivariate analysis revealed that alanine aminotrans-ferase level is an independent risk factor for long-term hospitalization in patients.Conclusion:The impact of viper bites on the levels of inflammation,liver function,and coagulation function in adult patients is positively correlated with the increased probability of a prolonged hospital stay,with the indication of alanine aminotransferase being particularly prominent.
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