Application value of metoprolol combined with daglizin in improving cardiac function and ventricular remodeling in patients with acute myocardial infarction after percutaneous coronary intervention
Objective:To discuss the application value of metoprolol combined with daglizin in improving car-diac function and ventricular remodeling in patients with acute myocardial infarction(AMI)after percutaneous cor-onary intervention(PCI).Methods:A total of 86 patients with AMI-PCI from January 2022 to October 2023 were selected and divided into experimental group(43 cases)and control group(43 cases)according to a random table.Patients in the control group were given metoprool+conventional treatment,and patients in the experimental group were given combined treatment with daglizin on this basis.The cardiac function(left ejection fraction[LVEF],heart index[CI],stroke output[SV]),ventricular remodeling(left ventricular end-diastolic volume[LV-EDV],left ventricular end-systolic volume[LVESV],left ventricular end-diastolic diameter[LVEDD])and labo-ratory parameters(N-terminal B-type natriuretic peptide precursor[NT-proBNP],hypersensitive C-reactive pro-tein[hs-CRP],interleukin-6[IL-6]),adverse cardiovascular events and adverse events were compared between the two groups.Results:After treatment,the LVEF,CI and SV of the two groups were significantly higher than those before treatment,and the LVEF,CI and SV in the experimental group were significantly higher than those in the control group(P＜0.05).After treatment,the LVEDV,LVESV,LVEDD,NT-proBNP,hs-CRP and IL-6 of the two groups were significantly lower than those before treatment,and LVEDV,LVESV,LVEDD,NT-proBNP,hs-CRP and IL-6 in the experimental group were significantly lower than those in the control group(P＜0.05).The incidence of adverse cardiovascular events in the experimental group was significantly lower than that in the control group(P＜0.05).The adverse events rate of the two groups was basically the same(P＞0.05).Conclusion:Metoprolol combined with daglizin can improve cardiac function and ventricular remodeling in patients with AMI-PCI,which is beneficial for prognosis improvement,and it is worthy of clinical promotion.
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