Early sustained hemoperfusion in acute acaricide poisoning:two cases report and literature review
The incidence of acute chlorfenapyr poisoning has gradually increased in recent years.The fatality rate is very high due to the lack of specific clinical manifestations in the early stage of poisoning,the existence of poisoning"latent period"and delayed toxic reaction,created the illusion of disease stability for patients and clini-cians.Besides,no specific antidote and other reasons for acute chlorfenapyr poisoning,although clinicians have taken a variety of measures for the treatment of patients,including gastric lavage,fluid infusion and excretion pro-motion,and energy supplementation,the case fatality rate remains high.As one of the effective ways to remove toxicants,early continuous hemoperfusion needs to be further evaluated in the treatment of acute fipronil poison-ing.This article collects 2 patients with acute chlorfenapyr poisoning admitted to the Emergency Department of the Second People's Hospital of Hefei,and summarizes and analyzes 37 cases of acute chlorfenapyr poisoning from around the world.The clinical characteristics,examination results,treatment plan and prognosis of acute chlorfe-napyr poisoning were analyzed,and the experience and lessons of treatment were summarized to guide the clinical treatment of acute chlorfenapyr poisoning.