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急性虫螨腈中毒早期持续血液灌流2例报道及文献回顾

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近年来,急性虫螨腈中毒发病率逐渐增加,由于中毒患者早期缺乏特异性临床表现,存在中毒"潜伏期"和迟发性毒性反应,给患者和临床医生造成病情稳定的假象;且虫螨腈中毒无特效解毒剂,虽然临床医生为救治中毒患者采取了包括洗胃、补液促排、补充能量等多种措施,但病死率仍居高不下.早期持续血液灌流作为清除毒物的有效方式之一,在治疗急性虫螨腈中毒的效果尚需进一步评估.本文收集了合肥市第二人民医院急诊科收治的2例急性虫螨腈中毒患者,并结合国内外文献报道的37例急性虫螨腈中毒患者的临床资料进行总结分析,包括急性虫螨腈中毒的临床特点、检查结果、治疗方案和预后等,总结治疗方法和救治经验教训,指导急性虫螨腈中毒患者的临床治疗.
Early sustained hemoperfusion in acute acaricide poisoning:two cases report and literature review
The incidence of acute chlorfenapyr poisoning has gradually increased in recent years.The fatality rate is very high due to the lack of specific clinical manifestations in the early stage of poisoning,the existence of poisoning"latent period"and delayed toxic reaction,created the illusion of disease stability for patients and clini-cians.Besides,no specific antidote and other reasons for acute chlorfenapyr poisoning,although clinicians have taken a variety of measures for the treatment of patients,including gastric lavage,fluid infusion and excretion pro-motion,and energy supplementation,the case fatality rate remains high.As one of the effective ways to remove toxicants,early continuous hemoperfusion needs to be further evaluated in the treatment of acute fipronil poison-ing.This article collects 2 patients with acute chlorfenapyr poisoning admitted to the Emergency Department of the Second People's Hospital of Hefei,and summarizes and analyzes 37 cases of acute chlorfenapyr poisoning from around the world.The clinical characteristics,examination results,treatment plan and prognosis of acute chlorfe-napyr poisoning were analyzed,and the experience and lessons of treatment were summarized to guide the clinical treatment of acute chlorfenapyr poisoning.

pesticidepoisoningchlorfenapyrtreatmentearly continuous hemoperfusion

徐礼友、骆佳艳、季流、程松、李海山

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合肥市第二人民医院急诊科(合肥,230000)

杀虫剂 中毒 虫螨腈 治疗 早期持续血液灌流

2024

临床急诊杂志
华中科技大学同济医学院

临床急诊杂志

CSTPCD
影响因子:0.652
ISSN:1009-5918
年,卷(期):2024.25(7)