Research progress on the mechanism and clinical treatment of intestinal barrier injury in heat stroke
In the past decade,climate change and human activities have led to an increasing frequency and se-verity of extreme weather events worldwide.Frequent heatwaves have brought about numerous issues for humani-ty,with the incidence of heat stroke-related deaths and disabilities showing a rising trend.Heat stroke is an acute illness that can lead to fatalities,characterized by a core symptom of body temperature exceeding 40℃ accompa-nied by central nervous system dysfunction.During the onset of heatstroke,intestinal barrier injury is considered to be the initiating factor for systemic inflammatory response syndrome and multiple organ dysfunction syndrome.This article provides a review of intestinal barrier injury induced by heat stroke and serves as a reference for the treatment of heat stroke in clinical practice.