Risk factors of postoperative acute kidney injury in elderly patients undergoing radical gastrectomy
Objective To analyse the risk factors of acute kidney injury(AKI)in elderly patients undergoing gastrectomy for gastric cancer.Methods The clinical data of 691 elderly patients,563 males and 128 females,aged ≥ 65 years,ASA physical grade Ⅰ to Ⅲ,who with gastrectomy for gastric cancer were retrospectively analyzed.Clinical data collected included sex,age,body weight,BMI,ASA physical status,preoperative comorbidities,history of alcohol and smoking history,operation duration,use of drugs,fluid intake and output,urine output,postoperative length of stay,total cost of hospitalization,and so on.According to the occurrence of AKI,the patients were divided into two groups:AKI group and non-AKI group.Multivariable logistic regression was used to determine the risk factors for AKI.Results Sixteen pa-tients(2.3%)developed AKI.Multivariate logistic regression showed that coronary heart disease(OR=5.587,95%CI 1.355-23.029,P=0.017)and lower urine output(OR=0.997,95%CI 0.995-1.000,P=0.023)were independent risk factors of AKI in aged patients.Conclusion Coronary heart disease and lower urine output were independent risk factors of AKI in elderly patients undergoing gastrecto-my.