Electroencephalographic mechanisms of loss of consciousness induced by propofol
Electroencephalography can continuously record the spontaneous and rhythmic electrical activity of local neurons in the brain region in real time and evaluate the functional state of the brain,which is a tool for monitoring brain activity.It has been widely used in the research fields of psychology,cognitive function and consciousness,which provides a new approach to study the mechanism of action of general an-esthetic drugs.Propofol is widely used in clinical practice,and its molecular mechanism has been deeply studied.The neural network mechanism of loss of consciousness induced by propofol is still unclear.This ar-ticle reviews the changes of electroencephalogram characteristics(including power spectrum,complexity,microstate,the functional connectivity,and brain network topology characteristics change)and corres-ponding brain functional changes of loss of conscionsness induced by propofol,the common general anesthet-ic,to provide a new idea for further research on the mechanism of action of anesthetic drugs and the depth of anesthesia monitoring.
ElectroencephalographyPropofolLoss of consciousnessBrain function
NETL
NSTL
万方数据
维普
