Efficacy and safety of electroacupuncture in the treatment of postoperative nausea and vomiting after gynecological surgery:a meta-analysis
王彩红 1魏晓涛 2赵永强 3薛建军 4徐紫清 4崔一阳 1周婷1
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作者信息
1. 730000 兰州市,甘肃中医药大学第一临床医学院
2. 甘肃省中医院骨科
3. 甘肃省中医院泌尿外科
4. 甘肃省中医院麻醉疼痛医学中心甘肃省中西医结合麻醉临床医学研究中心
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摘要
目的 系统性评价电针(EA)治疗妇科手术后恶心呕吐(PONV)的有效性和安全性.方法 计算机检索 PubMed、Cochrane Library、Web of Science、Embase、中国知网(CNKI)、万方数据库、中国生物医学文献数据库(CBM)等,检索时间为建库至2022年12月,纳入EA用于治疗妇科手术PONV的随机对照试验,采用RevMan5.3软件进行Meta分析.结果 共纳入14篇文献,患者958例,其中EA组477例,对照组481例.与对照组比较,EA组术后0～48 h PONV发生率明显降低(RR=0.55,95％CI 0.47～0.65,P＜0.001),术后 48 h 内 PONV 评分明显降低(MD=-0.40 分,95％CI-0.65～-0.16分,P=0.001),术后补救性止吐发生率明显降低(RR=0.28,95％CI 0.16～0.51,P＜0.001).结论 采用EA可明显降低妇科手术PONV发生率和补救性止吐的发生率.
Abstract
Objective To systematically evaluate the efficacy and safety of electroacupuncture(EA)in the treatment of postoperative nausea and vomiting(PONV)after gynecological surgery.Methods PubMed,Cochrane Library,Web of Science,Embase,China national knowledge infrastructure(CNKI),Wanfang database,and China biomedical literature database(CBM)were systematically searched.The re-trieval period was from the establishment of the database to December 2022.Relevant randomized controlled trials on EA for the treatment of PONV in gynecological surgery were collected.RevMan 5.3 software was used for meta-analysis.Results Fourteen randomized controlled trials were accommodated,including 958 patients,477 patients in the EA group and 481 patients in the control group.Compared with the control group,the incidence of PONV was significantly lower in group EA at 0-48 hours postoperatively(RR=0.55,95％CI 0.47 to 0.65,P＜0.001),and the PONV scores were significantly lower in the postopera-tive period within 48 hours in group EA(MD=-0.40 scores,95％CI-0.65 to-0.16 scores,P=0.004),the incidence of postoperative remedial antiemetic were significantly lower(RR=0.28,95％CI 0.16 to 0.51,P＜0.001).Conclusion EA can reduce the incidence of PONV and the incidence of re-medial antiemetic after gynecologic surgery.
关键词
电针/妇科手术/术后恶心呕吐/Meta分析
Key words
Electroacupuncture/Gynecological surgery/Postoperative nausea and vomiting/Meta-analysis
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万方数据