首页|艾司氯胺酮防治围术期抑郁的研究进展

艾司氯胺酮防治围术期抑郁的研究进展

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抑郁是围术期常见的情绪障碍,无论是术前并存抑郁还是术后新发抑郁,均会影响患者术后康复,且目前缺乏有效的干预措施.相关研究表明,艾司氯胺酮可以缓解围术期抑郁.本文对围术期抑郁、艾司氯胺酮及其抗抑郁机制、艾司氯胺酮在防治围术期抑郁中的应用及其相关不良反应进行综述,以期为艾司氯胺酮的临床应用及围术期抑郁的防治提供参考.
Research progress in the prevention and treatment effect of esketamine on perioperative depression
Depression is a common mood disorder in perioperative period.Both preoperative depres-sion and postoperative new depression can affect postoperative rehabilitation of patients,and there is a lack of effective intervention measures.Related studies have indicated that esketamine can alleviate perioperative depressive symptoms.In order to provide references for clinical work and reduce the occurrence of periopera-tive depression,this review summarizes perioperative depression,esketamine and its anti-depression mecha-nism,the application of esketamine in prevention and treatment of perioperative depression and its related adverse reactions.

EsketamineDepressionPerioperative period

娄雪杰、邱迪、张广芬、杨建军

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450000 郑州大学第一附属医院麻醉与围术期医学部

山东第一医科大学附属省立医院麻醉科

艾司氯胺酮 抑郁 围术期

国家自然科学基金区域联合重点项目

U23A20421

2024

临床麻醉学杂志
中华医学会南京分会

临床麻醉学杂志

CSTPCD北大核心
影响因子:2.225
ISSN:1004-5805
年,卷(期):2024.40(6)
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