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七氟醚对发育期哮喘患儿气道作用的研究进展

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哮喘是一种患儿发育期常见的气道慢性炎症性疾病,严重影响患儿的生活质量和生命健康.在麻醉药物和手术刺激等多种因素的影响下,哮喘在围术期易被诱发及加重.七氟醚是目前小儿麻醉中最常用的吸入麻醉药,不同浓度的七氟醚可对哮喘患儿气道产生不同的效应.本文综述不同浓度七氟醚对哮喘患儿气道力学、气道炎症以及气道重塑作用的相关研究进展,为哮喘患儿的围术期用药及治疗方案提供参考.
Research progress on airway effects of sevoflurane in children with developing asthma
Asthma is a common chronic inflammatory airway disease during childhood development,which seriously affects the quality of life and life health of children.Under the influence of various factors such as anesthetic drugs and surgical stimulation,asthma is easily induced and aggravated in the periopera-tive period.Sevoflurane is the most commonly used inhalation anesthetic in pediatric anesthesia,and differ-ent concentrations of sevoflurane can produce different effects on the airway of children with asthma.In this paper,the effects of sevoflurane on airway mechanics,airway inflammation,and airway remodeling in chil-dren with asthma were reviewed,providing reference for future intraoperative medication and treatment of children with asthma.

SevofluraneDeveloping asthmaAirway mechanicsAirway inflammationAirway re-modeling

冉颖、刘德行

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563000 贵州省遵义市,遵义医科大学附属医院麻醉科

七氟醚 发育期哮喘 气道力学 气道炎症 气道重塑

2024

临床麻醉学杂志
中华医学会南京分会

临床麻醉学杂志

CSTPCD北大核心
影响因子:2.225
ISSN:1004-5805
年,卷(期):2024.40(6)
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