Application progress of remimazolam in general anesthesia
Remimazolam is a new type of ultra-short-acting benzodiazepine,which has the advanta-ges of rapid onset,rapid metabolism,no accumulation,stable hemodynamics,light respiratory inhibition,independent of liver and kidney metabolism,inactive metabolites,and rapid antagonism by specific antago-nist flumazenil.Due to its functional characteristics,remazolam is extensively utilized in painless endoscopic procedures,sedation in intensive care units,and regional block anesthesia assisted sedation.Currently,the utilization of remazolam in general anesthesia is on the rise,with numerous studies confirming its safety and efficacy in the induction and maintenance of general anesthesia.This article reviews the pharmacological properties of remimazolam and its clinical studies progress on induction and maintenance of general anesthe-sia,and provides reference for its clinical anesthesia application.
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