Multicentric infantile myofibromatosis:a case report
A case of multicentric infantile myofibromatosis is reported.A 5-month-old male infant presented with multiple nod-ules on the skin,which appeared at six days after birth and gradually enlarged thereafter.Dermatological examination showed several round,red nodules that were scattered across his body surface.The nodules were well-defined and had a smooth sur face with telangiectasia,accompanied by a hard texture.His previous skull computed tomography and chest X-ray results at another hospital showed no obvious bone destruction.Histopathological examination showed that the epidermis was mostly nor-mal,and the tumour was located in the middle and lower dermis.The tumour was composed of two types of cells:spindle cells,which exhibited nodular and vortex-like arrangement,eosinophilic cytoplasm,and elongated or vesicular nuclei;and primitive mesenchymal cells,which had a round or small polygonal shape and were distributed in solid sheets or hemangiopericytoma in the blood vessels,without necrosis or cell atypia.Immunohistochemistry results showed positive smooth muscle actin.A diagno-sis of multicentric infantile myofibromatosis was made.Several nodules subsided after three months of follow-up.
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